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Geodon has been the best antipsychotic for me from a physical point of view - I lost ten kilograms that I had put on while Zyprexa. Concentration is not very good on it though - I cannot study as well as I did on Zyprexa. I lowered the dose to 80mg and suddenly it was not sufficient and I started getting symptoms again. Now I am on 120mg and symptoms have gone away but am a bit hazy and unclear, struggling to concentrate and wanting to sleep late in the mornings. I want to try 100mg to see if I will stay stable on this dose.

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SocCog training (in a single-arm design), CHR participants showed reduced activity and increased connectivity in the emotion recognition network.

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PET) scans were performed before and after dose reduction.

Methods: This talk will briefly review the current results of trials of novel therapies for schizophrenia, using publically available data.

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Pupil dilation and changes in subjective ratings of CS also indexed conditioning.

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Benattia I, Addington D, Pantelis C, Dineen M, Murray S: Ziprasidone vs risperidone in schizophrenia: an 8-week, double-blind trial with 44-week continuation (abstract).

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Background: Disaggregating clinical clusters such as cognitive performance within schizophrenia (SCZ) will assist in identifying pathological mechanisms and possible biomarkers and help devise appropriate treatments.

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Due to their complexity and variability, disorders involving auditory processing lack a consistent definition and diagnostic criteria.

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Results: We next measured levels of glutamate transport complex proteins in subcellular fractions and found increases in the EAAT2B isoform of EAAT2 in a fraction containing extrasynaptic membranes, and increased aconitase1 in a mitochondrial fraction in schizophrenia.

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Methods: 40 healthy controls and 37 individuals with schizophrenia underwent a computerized psychological challenge involving two tasks (mirror tracing and mental arithmetic) designed to be frustrating and obnoxious.

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The use of the risk prediction analytes to understand molecular pathways leading to psychosis will be further explored.

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In a meta-analysis, we found that the cytokine interleukin-6 (IL-6) may be a state maker for relapse in schizophrenia: blood IL-6 levels are increased in episodes of acute psychosis, and decreased following antipsychotic treatment for relapse.

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Comparative effectiveness of depot and oral second generation antipsychotic drugs in schizophrenia: A nationwide study in Hungary.

It is a core feature of autism that social interactions appear to be far less rewarding for autistic children compared to typically developing children.

However, it has been proposed that this drug's efficacy in schizophrenia is mediated through a combination of dopamine type 2 (D 2) and serotonin type 2 (5HT 2) antagonism.

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Sex differences in the effect of four second-generation antipsychotics on QTc interval in patients with schizophrenia.

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Patients with current tardive dyskinesia could enroll, but the randomization scheme prevented their assignment to treatment with perphenazine.

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No data specifically addressing iloperidone use in humans during pregnancy are available.

The ancient Greek philosophers taught that the 5 pillars of their civilization were: wisdom, courage, helping others, self-control, and justice.

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Methods: Functional magnetic resonance imaging was performed on 15 participants with schizophrenia and 24 matched healthy controls during the performance of a prospective memory task (Halahalli et al 2014) where the delayed intention was triggered by an endogenous cue generated by incremental updating of working memory.

Conclusion: Clinically plausible subgroups of patients can be detected using a simple model of inter-regional connectivity.

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